Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

In this study, the influence of amphetamines on GABA (gamma amino butyric acid) was studied in the rat brain (striatum, cortex and hippocampus). According to literature, an increase in GABA is expected after 4 hours, whereas normalization occurs within 24 hours. Rats were therefore injected intraperitoneally with 30mg/kg amphetamine and necropsied after 4 and 24h. Salt solution was injected as a negative control in control animals. Brain samples were derivated by means of OPA/ß-mercaptoethanol and iodoacetamide, followed by HPLC and electrochemical analysis. First, there was made a linearity curve with the standards of GABA. And when the samples were measured, the concentration can be calculated with the linearity curve. For this results there can be concluded that amphetamines have no effect on GABA concentrations in the different brain levels. But because there were too less samples, the conclusion is not very reliable. Because of the less results, statistical analysis could not be done. In dit onderzoek werd de invloed van amfetamines op GABA (gamma amino boterzuur) bestudeerd in de hersenen van de rat (striatum, cortex en hippocampus). Volgens de literatuur wordt een stijging van GABA verwacht na 4 uur, terwijl normalisatie voorkomt na 24 uur. Hiervoor werden de ratten intraperitonaal geïnjecteerd met 30mg/kg amfetamine en gedissecteerd na 4 en 24 uur. De zoutoplossing werd geïnjecteerd als negatieve controle in controle dieren. Stalen van de hersenen werden gederivatiseerd met OPA/ß-mercaptoethanol en joodacetamide, gevolgd door HPLC en electrochemische detectie. Allereerst werd er een lineariteitscurve gemaakt met de standaarden van GABA. En wanneer de stalen gemeten werden, kon de concentratie berekend worden door middel van de lineariteitscirve. Voor deze resultaten kan er geconcludeerd worden dat amfetamines geen effect hebben op de GABA concentraties in de verschillende hersendelen. Maar omdat er te weinig stalen gemeten werden is de conclusi...

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

With the surge of new distribution technologies of non-linear television, for a large part brought about by Netflix, traditional practices concerning television viewing and television industry lore have been challenged. More often, people are choosing to figuratively cut the cord and cancel their linear television subscriptions. These trends are causing broadcasting networks anxieties. The altering behavior of the audience has forced networks and broadcasting organizations to revise their established practices and to innovate. The television industry has been marked by increasing commercialization, fragmentation and platformization. Ever since the late 1990s, Public Service Broadcasters have experienced threats, back then because of the rise of commercial channels and networks. During the last decade, public service broadcasters around Europe have experienced new threats, and their existence and value in society was questioned. Moreover, international conglomerates have entered the local media markets and threaten to overshadow domestic companies. Local commercial networks answered these threats by establishing their own non-linear distribution portals, often subscription-based and including a ‘local Netflix’. For public service broadcasters, it is more difficult to find a sustainable balance between commercial goals and innovation, as they have to answer to more restrictions in accordance with the government. In August 2022, Flemish Public Service Broadcaster VRT rebranded their non-linear internet distribution portal, VRT NU, to VRT MAX after it became apparent that it did not serve the needs of a large demographic, namely those between the ages of 15 and 35, thus including Generation Z. To breach this lacuna in audience, VRT MAX targets this group specifically, thereby consolidating its position in society and as Public Service Media. This thesis first looked into the various developments that took place in the television industry, particularly after the arrival of Netflix. Then, the research focused on evolution within the Flemish ecosystem. In the final part, a case study evaluated in which ways VRT MAX as a rebranded portal has contributed to the consolidation of VRT as Public Service Media in the Flemish media ecosystem, which has been disrupted by commercialization, fragmentation and platformization. The case study will follow the strategies public service media across Europe have taken in reaction to international subscription-based video-ondemand services, a typology that stems for Philip Napoli but which was adapted by D’Arma, Raats, and Steemers. From this case study was concluded that VRT MAX is still very new in the media ecosystem, and can contribute to the consolidation of the position of VRT drawing on the strategies of differentiation, mimicry and collaboration.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)